PRINCIPAL RESEARCH ASSOCIATE – T CELL IMMUNOTHERAPY

 

NOTICE OF FILING OF APPLICATION BY GENEIUS BIOTHECHNOLOGY, INC.

UNDER THE U.S. DEPARTMENT OF LABOR’S PARMANENT LABOR CERTIFICATION PROGRAM

 

POSITION TITLE:         PRINCIPAL RESEACRH ASSOCIATE-T CELL IMMUNOTHERAPY

LOCATION:                  NATICK, MASSACHUSETTS                                

JOB DUTIES:                CANDIDATE WILL LEAD AND PARTICIPATE IN THE DEVELOPMENT OF OUR NOVEL IMMUNOTHERARY APPROACH AS PART                                        OF OUR EXPERIENCED PRODUCT DEVELOPMENT TEAM.

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CANDIDATE WILL CONDUCT AND SUPERVISE RESEARCH INTO TWO PROJECTS:

1) GNS-TEBV-001 PROJECT DESIGN AND DEVELOP T-CELLS FOR THE TREATMENT OF CANCER (60%)

2) COVID-19 PROJECT DESIGN AND DEVELOP T-CELLS AGAINST COVID-19 VIRUS (40%)

 

DUTIES AND PERCENTAGE OF TIME DEVOTED TO EACH PROJECT:

• DESIGN AND DEVELOP:

          1. APPROACHES TO PRIME, GROW AND EXPAND T CELLS FOR SMALL- AND LARGE-SCALE TISSUE CULTURES (10%)

          2. ASSAYS TO CHARACTERIZE T CELL SUBSETS IN HUMAN T CELL LINES AND PATIENT SAMPLES (10%)

          3. CELL-BASED ASSAYS TO ASSESS T CELL FUNCTION (10%)

• WRITE PROTOCOLS AND STANDARD OPERATING PROCEDURES (SOPS) FOR CLOSED-SYSTEM MANUFACTURING (10%)

• PREPARE AND PRESENT EXPERIMENTAL METHODS AND RESULTS (10%)

• PREPARE TECHNICAL REPORTS TO SUPPORT PROCESS DEVELOPMENT/IND FILING (15%)

• SUPERVISE AND TRAIN RESEARCH ASSOCIATE (15%)

• FACILITATE TECHNOLOGY TRANSFER OF MANUFACTURING PROCESS TO GOOD MANUFACTURING PROCESS (GMP) AT UNIVERSITIES AND
  COMMERCIAL CONTRACT MANUFACTURERS (20%)

 

EDUCATION/EXPERIENCE:  BA in Biology or Neuroscience plus 2 years of experience Biology Laboratory Research Position.

 

SPECIAL REQUIREMENTS:  GOOD MANUFACTURING PRACTICE-LAB EXPERIENCE WITH CLOSED-SYSTEM MANUFACTURING OF T-CELL

PRODUCTS; HANDS-ON EXP SETTING UP TISSUE CULTURES, PERFORMING FLOW CYTOMETRY-BASED ASSAYS, AND ELISPOT ASSAYS.  EXPERIENCE WRITING EXPERIMENTAL PROTOCOLS.  AVAILABLE TO WORK WEEKENDS AND OVERTIME IF NECESSARY

 

DOMESTIC TRAVEL TO UNIVERSITIES AND COMMERCIAL MANUFACTURING FACILITIES MAY BE REQUIRED.

 

WORK SCHEDULE:     8 am – 5 pm

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CONTACT PERSON:   Send resumes and references to Dr. Alfred Slanetz at: aslanetz@geneius.com